In vitro pilot study comparing a novel implantoplasty sonic instrumentation protocol with a conventional protocol using burs.

BACKGROUND AND OBJECTIVES: The aim of implantoplasty (IP) is to remove titanium implant layers that have been contaminated and to smoothen the implant surfaces so they retain less plaque. However, existing IP methods are very invasive and reduce implant wall thickness. AIM: To investigate the suitability of novel sonic tips in IP and to compare this novel protocol with conventional abrasive procedures. MATERIALS AND METHODS: Thirty dental implants (Ø 4.1 mm, 10 mm length) were distributed in three groups and investigated according to the protocol of Sivolella et al., with modifications to the instrument's feed rate, the applied contact force, and the speed of implant rotations per minute. The upper third of the implant was processed with a diamond-coated bur (BUR) or novel non-diamond-coated sonic tips (AIRSCALER). After standardized IP, the surfaces were analyzed by tactile profilometry and scanning electron microscopy (SEM). Changes in implant weight, implant material loss, and implant fracture strength were assessed. RESULTS: The mean roughness (Ra , Sa ), implant material loss, and change in implant weight were significantly lower in the AIRSCALER group than in the BUR group, whereas the mean compression resistance values were significantly higher in the AIRSCALER group than in the BUR group. CONCLUSIONS: IP with uncoated sonic tips smoothes the surfaces and reduces structural loss of the implant in the area of microthreads. This new IP method could be of great clinical importance, especially for implants with microthreads and reduced diameter or wall thickness.

Immediate loading of dental implants in edentulous mandibles using Locator attachments or Dolder bars: A 9-year prospective randomized clinical study.

AIM: To evaluate the long-term survival, incidence of prosthetic/technical and biological complications and the oral-health-related quality of life in patients with an edentulous mandible who were fitted with overdentures on two immediately loaded implants in the symphyseal area. MATERIALS AND METHODS: Forty-six patients with edentulous mandibles received two immediately loaded implant-retained dentures with either two Locator attachments or egg-shaped bar attachments. Implant outcomes were recorded after a period of observation of 9 years and included prosthetic complications, modified gingiva index (mGI), modified plaque index (mPI), oral health impact profile (OHIP-G) and radiographic estimation of bone loss. RESULTS: In 2020/2021, 27 patients with 54 implants were still available for follow-up. In total, nine implants in six patients were lost. Survival was 89.1% in the bar group and 91.3% in the Locator group. Implant success was 84.6% in the Locator group and 76.9% in the bar group. The mPI values were significantly higher in the bar group than in the Locator group, whereas no difference was seen in the mGI values. During the observation period, 152 prosthetic complications occurred, but the OHIP-G score did not differ significantly. CONCLUSIONS: There was no difference in implant survival between Locator or joint bar attachments over a 9-year observation period. Joint bar attachments were associated with slightly more complications, while patients in the Locator group were able to maintain better oral hygiene. The study was registered in the German Register of Clinical (Trials DRKS00004245).

Survival and success of tooth-implant-supported and solely implant-supported double-crown-retained overdentures: A prospective study over a period of up to 11 years.

OBJECTIVES: To investigate the long-term performance, over a period of up to 11 years, of tooth-implant-supported and solely implant-supported double-crown-retained overdentures (DCRDs) for complete restoration of the jaw. MATERIALS AND METHODS: Between 2002 and 2015, patients were consecutively enrolled in the study at Heidelberg University Hospital's Department of Prosthodontics. Scheduled and unscheduled visits were both documented on standardized forms. Kaplan-Meier curves were used to evaluate survival and success of the DCRDs. Mixed effects Cox regression was used to identify the potential effects of age, sex, jaw, location of implants, and the number of abutment teeth on the success of the DCRDs. RESULTS: One hundred and thirty-nine DCRDs were placed in 126 participants (mean age: 65.6 ± 9.1 years; 76 [60.3%] men). The mean follow-up period was 4.2 years. Fifty-three (38%) DCRDs were solely implant-supported (213 implants) and 86 (62%) were tooth-implant-supported (239 teeth and 199 implants). Cumulative five-year survival was 96.2% in the implant-supported group and 97.7% in the tooth-implant-supported group. Simultaneous consideration of failures and severe complications revealed cumulative five-year success of 88.2% for implant-supported DCRDs and 81.9% for tooth-implant-supported DCRDs, with no significant difference between the two types of restoration. Cox regression analysis revealed a greater risk of major complications (hazard ratio: 4.87, p = .04) for maxillary DCRDs than for mandibular DCRDs. CONCLUSIONS: Although the study design has limitations, the results show that tooth-implant-supported and solely implant-supported DCRDs are both recommendable treatment options. After a mean follow-up of 4.2 years, survival and success were high. However, minor complications were common and required much aftercare. CLINICAL TRIAL REGISTRATION: This study started in 2005 and was approved by the local review board of the University of Heidelberg. In 2005, clinical trial registration was not yet common. For this reason, the study was not registered.

Maxillary implant overdentures on two or four implants. A prospective randomized cross-over clinical trial of implant and denture success and survival.

OBJECTIVES: To determine implant survival and success of four conventionally but initially asynchronously loaded implants in implant-supported overdentures for the edentulous maxilla, in participants with opposing mandibular two-implant overdentures. MATERIAL AND METHODS: Twenty-six participants received four implants in the region of the maxillary canines and molars. After healing, 24 of these participants (mean age: 68.3 years) were randomly allocated to one of two treatment groups, and the adapted overdenture was attached to two unsplinted cylindrical attachments. The other two matrixes remained unattached to the implants for 3 months. After this period, the other two implants were loaded for 3 months (cross-over design). Then, all four implants were loaded for another 3 months. Kaplan-Meier curves were used to evaluate survival and success of implants and dentures. RESULTS: During the active prosthetic study phase, three participants lost one implant. Two participants lost three implants during the recall period. Implant survival after loading was 93.8% after a mean observation period of 3.1 years. Denture survival was 100%, but denture success was 95.8%, due to major prosthetic complications. Most participants preferred four implants to two. CONCLUSIONS: Within the limitations of the study, it can be concluded that maxillary implant overdentures on two or four implants are both recommendable treatment options. Two posterior implants are not superior to two anterior implants under overdentures retained by unsplinted cylindrical attachments. Implant and prosthetic complications and aftercare measures are common but are mostly easy to handle. However, 23 of the 24 participants preferred the 4-implant maxillary overdenture.

Long-term chipping and failure rates of implant-supported and combined tooth-implant-supported metal-ceramic and ceramic fixed dental prostheses: A cohort study.

STATEMENT OF PROBLEM: Combined tooth-implant-supported fixed dental prostheses have been associated with an increased risk of long-term failure. Furthermore, high chipping rates have been reported for ceramic fixed dental prostheses. However, clinical data are sparse. PURPOSE: The purpose of this observational cohort study was to evaluate the chipping and failure rates of metal-ceramic and ceramic implant-supported and combined tooth-implant-supported fixed dental prostheses. MATERIAL AND METHODS: Four hundred thirty-four fixed dental prostheses placed in 324 patients (mean age: 60.8 years) were selected from a prospective clinical long-term study comprising 213 implant-supported fixed dental prostheses, 66 implant-supported cantilever fixed dental prostheses, and 155 tooth-implant-supported fixed dental prostheses. Metal-ceramic fixed dental prostheses (n=260) were fabricated with a high noble metal alloy (n=225) or Co-Cr base metal alloy (n=35) frameworks. Ceramic fixed dental prostheses (n=174) were all zirconia based and had monolithic (n=68), completely veneered (n=43), or partially veneered frameworks (n=63). Kaplan-Meier curves were used to estimate the survival probability and the chipping-free survival rate of the fixed dental prostheses. RESULTS: During the observation period of 0.5 to 12.6 years (mean: 4.26 years), 17 fixed dental prostheses failed because of implant failure (n=6), tooth loss (n=5), major chipping (n=5), or abutment screw loosening (n=1). Survival probability was 96% after 5 years and 91% after 10 years. Cox regression analysis showed that age, sex, fixed dental prosthesis location, type of fixed dental prosthesis support, and fixed dental prosthesis material had no significant effect on fixed dental prosthesis failure. Chipping (n=61) was significantly affected by the framework material and type of veneer (P=.001). After 5 years, the greatest incidence of chipping (39%) was observed for zirconia fixed dental prostheses with a complete veneer compared with an 18% incidence of chipping for metal-ceramic fixed dental prostheses with a high noble metal framework. A lower incidence of chipping was observed for zirconia fixed dental prostheses with a partial veneer or monolithic design. CONCLUSIONS: Implant-implant-supported and combined tooth-implant-supported fixed dental prostheses have promising long-term survival rates. Chipping seems to occur less frequently in monolithic or partially veneered fixed dental prostheses than in fixed dental prostheses with complete veneers.

Effect of bone quality and quantity on the primary stability of dental implants in a simulated bicortical placement.

OBJECTIVES: Conventional dental implants inserted in the molar region of the maxilla will reach into the sinus maxillaris when alveolar ridge height is limited. When surgery is performed without prior augmentation of the sinus floor, primary stability of the implant is important for successful osseointegration. This study aimed at identifying the impact of bone quality and quantity at the implantation site on primary implant stability of a simulated bicortical placement. MATERIALS AND METHODS: In our in vitro measurements, bone mineral density, total bone thickness and overall cortical bone thickness were assessed by micro-computed tomography (µCT) of pig scapulae, which resembled well the bicortical situation found in human patients. Dental implants were inserted, and micromotion between bone and implant was measured while loading the implant with an axial torque. RESULTS: The main findings were that primary implant stability did not depend on total bone thickness but tended to increase with either increasing bone mineral density or overall cortical bone thickness. CLINICAL RELEVANCE: Limited bone height in the maxilla is a major problem when planning dental implants. To overcome this problem, several approaches, e.g. external or internal sinus floor elevation, have been established. When planning the insertion of a dental implant an important aspect is the primary stability which can be expected. With other factors, the dimensions of the cortical bone might be relevant in this context. It would, therefore, be helpful to define the minimum thickness of cortical bone required to achieve sufficient primary stability, thus avoiding additional surgical intervention.

Resistance to Fracture in Fixed Dental Prostheses Over Cemented and Screw-Retained Implant-Supported Zirconia Cantilevers in the Anterior Region: An In Vitro Study.

PURPOSE: To evaluate the resistance to fracture in cantilevered fixed dental prostheses (cFDPs) of single implant-supported zirconia cantilevers in the anterior region. MATERIALS AND METHODS: Thirty-two cemented and solely screw-retained cFDPs consisting of an implant-supported crown replacing the central incisor and an attached cantilever unit in the position of the lateral incisor in the maxilla were constructed by computer-aided design (CAD) and machined by computer-aided manufacturing (CAM). For the cemented solution, a cFDP was designed on top of a customized abutment luted to an adhesive base. For screw-retained cFDPs, abutment, cement gap, and restoration of the cementable design were combined. All cFDPs were veneered manually on the facial side. Half of the samples underwent artificial aging (thermocycling and chewing simulation) before fracture tests were conducted with loads applied to the pontic either parallel to the implant axis (axial loading on the pontic) or tilted lingually by α = 45 degrees (oblique loading on the pontic). Thus, there were eight groups differing in cFDP design, artificial aging, and load application (n = 8/group). If fracture (Fu,total) occurred within the implant components, the adhesive base was replaced by a cast CoCr base, and the cFDP's fracture resistance (Fu,cFDP) was also determined. Using statistical analyses (SPSS 24, IBM), factors affecting fracture resistance were identified. RESULTS: Fu,total was mainly correlated to screw fractures and therefore not affected by cFDP design. Oblique loading on the pontic (Fu,total = 231 N - 352 N), however, led to a significant (P < .001) decrease in ultimate load compared with axial loading on the pontic (Fu,total = 611 N - 815 N). In relation to Fu,total, Fu,cFDP was approximately twice as high for both loading conditions. CONCLUSION: When relating the results to maximum occlusal forces exerted in the maxillary anterior region, single implant-supported cFDPs can be a viable restorative treatment option.

The effect of transcrestal sinus-floor elevation without graft on the long-term prognosis of maxillary implants.

AIM: To evaluate the effects of (a) transcrestal sinus-floor elevation (TSFE) and (b) residual bone height on long-term implant survival. MATERIALS AND METHODS: Chi-squared and t tests were used for descriptive comparison of the groups. Kaplan-Meier survival curves and corresponding log-rank tests were used to investigate implant survival over time. Multivariable Cox regressions were performed for the total population and experimental group. RESULTS: A total of 634 patients received 648 implants with TSFE, while 674 implants without TSFE served as controls. Thirty implant failures occurred in the experimental group and 28 in the control group. Ten-year Kaplan-Meier survival curves for the 157 implants (24.3%) still under observation showed a probability of survival of 93.7% for the implants with TSFE and 92.9% for the 72 implants without TSFE (p = .678). The probability of 10-year survival of all implants in the experimental group decreased to 77.4% for implants placed in residual bone heights of 1-3 mm, compared with 95.7% for implant sites with bone heights of 4-6 mm and 97.6% for bone heights of >6 mm. CONCLUSIONS: Transcrestal sinus-floor elevation has no negative effect on the long-term implant survival. Membrane perforation or negligible bone height, however, reduces the probability of 10-year survival.

Long-term performance of implant-supported metal-ceramic and all-ceramic single crowns.

PURPOSE: To evaluate failure rates and incidence of chipping for metal-ceramic and all-ceramic implant-supported single crowns (SCs). METHODS: Six hundred and fifty-two implant-supported SCs placed in 404 patients (mean age: 57.8 years; 193 male; mean SCs per patient: 1.6) were evaluated up to 12.8 years. The frameworks of the SCs were made from Au alloys (n = 319), CoCr (n = 37), zirconia (n = 286), or lithium disilicate (n = 10). Full-coverage ceramic veneers were placed on 319 Au SCs, 34 CoCr SCs, and 92 zirconia SCs. One hundred and fifty-two monolithic zirconia SCs were not veneered. A partial veneer was placed on the buccal surface only of a further 42 zirconia SCs. RESULTS: A total of 26 failures were caused by loss of implants (n = 6), ceramic fractures and chipping (n = 15), loosening of the abutment (n = 4), or swallowing of a de-cemented SC (n = 1). Kaplan-Meier analysis revealed a probability of survival of 96% after five years and 92% after 10 years. A greater incidence of failure was observed for lithium disilicate and zirconia SCs than for metal-ceramic SCs (p < .05). Separate analysis of the most frequent complication, chipping (n = 61), revealed that zirconia and lithium disilicate frameworks were significant risk factors for chipping (p < 0.05). Furthermore, a significantly greater incidence of chipping was observed for SCs with full-coverage veneers than for monolithic zirconia SCs and for SCs with partial veneers (p < .05). CONCLUSION: Avoidance of full-coverage veneers significantly improves the clinical performance of implant-supported crowns, primarily reduces the incidence of chipping.

The up-to-11-year survival and success of implants and abutment teeth under solely implant-supported and combined tooth-implant-supported double crown-retained removable dentures.

OBJECTIVE: This retrospective analysis was designed to compare the survival and success of dental implants in solely implant-supported, double crown-retained removable dentures (DCRDs) and combined tooth-implant-supported DCRDs, due to a lack of data on the latter. MATERIAL AND METHODS: From 2002, patients were consecutively admitted for treatment at the Department of Prosthodontics, University of Heidelberg. Surgical and prosthodontic treatment and scheduled and unscheduled visits were recorded on standardized documentation forms. Kaplan-Meier analysis was used to estimate success (survival without major complications). Cox regression was applied to assess risk factors. RESULTS: From this clinical study, 139 DCRDs on 412 implants and 239 teeth met the inclusion criteria. Fifty-three dentures were implant-supported (213 implants). Eighty-six were supported by teeth and implants. The DCRDs were placed in 126 patients. After an observation period of up to 11.2 years (median: 4.2 years), total implant survival was 99.5% for tooth-implant-supported DCRDs and 93.4% for implant-supported ones. The estimated cumulative success was 97.2% (standard error/SE ± 1.2%) and 85.9% (SE ± 2.4%) at five years, respectively. Complications included implant or tooth loss, peri-implantitis, apical periodontitis and tooth fracture. In terms of abutments, results from multiple Cox regression revealed lower failure rates in tooth-implant-supported dentures (p = .04). No other risk factors were identified. CONCLUSIONS: Within the limitations of this study, survival and success are high for both treatment options. Combining teeth and implants in one DCRD might have a positive effect on the prognosis of the implant and the survival of remaining teeth.

Adaptation to new complete dentures-is the neuromuscular system outcome-oriented or effort-oriented?

OBJECTIVE: The aim of this study was to observe the adaptation strategy of the stomatognathic system during the adaptation of complete dentures, comprising masticatory parameters and subjective measures. Our hypothesis was that with new dentures, masticatory performance would increase while the effort of the system is kept constant. MATERIAL AND METHODS: Thirty-two patients received standardized new complete dentures. Masticatory performance tests were conducted with old dentures (T1), immediately after incorporation of new dentures (T2) and after an adaptation period of 3 months (T3). Patients habitually chewed the silicone-based artificial test food Optocal. The comminuted test food was analyzed and mean particle sizes (x50) were calculated. Simultaneously, surface EMGs of the anterior temporalis and masseter muscles were recorded. Specific (SMW) and total muscle work (TMW) were determined. Patients filled in the OHIP-49 questionnaire. Test conditions were compared using repeated-measures ANOVA with SPSS 22 (SPSS Inc.) RESULTS: Masticatory performance increased (P = 0.016) between old (x50 = 4.99 ± 0.28) and adapted new dentures (x50 = 4.80 ± 0.33). TMW deteriorated (P = 0.004) at T2 (from TMW1 = 119.77 ± 56.49 to TMW2 = 92.12 46.27), and increased again (P = 0.028) at T3 (TMW3 = 107.66 ± 44.65). OHIP scores decreased significantly in all subscales (P < 0.001…P = 0.046); the total score was reduced (P < 0.001) from 56.24 ± 29.05 (T1) to 34.66 ± 24.74 (T3). CONCLUSION: In complete denture wearers, masticatory performance improves over an adaptation period. Muscle work initially decreased before reaching its original level again after adaptation. Subjective parameters overestimated the functional improvements. CLINICAL SIGNIFICANCE: The subjective evaluation does not adequately reflect functional improvements. The assessment of function requires an adaptation period.

Effects of Cement, Abutment Surface Pretreatment, and Artificial Aging on the Force Required to Detach Cantilever Fixed Dental Prostheses from Dental Implants.

PURPOSE: To examine the in vitro effects of different cements, abutment surface preconditioning, and artificial aging on the maximum tensile force needed to detach cantilever fixed dental prostheses (FDPs) from dental implants with titanium abutments. MATERIALS AND METHODS: A total of 32 tissue-level implants were combined with standardized titanium abutments. For each test group, eight cantilever FDPs were fabricated using selective laser melting (cobalt-chromium [CoCr] alloy). The inner surfaces of the cantilever FDPs and half of the abutments were sandblasted and then joined by use of four different cements (two permanent and two semi-permanent) in two different amounts per cement. Subgroups were tested after either artificial aging (thermocycling and chewing simulation) or 3 days of water storage. Finally, axial pull off-tests were performed for each abutment separately. RESULTS: Cement type and surface pretreatment significantly affected decementation behavior. The highest retention forces (approximately 1,200 N) were associated with sandblasted abutments and permanent cements. With unconditioned abutments, temporary cements (Fu < 100 N), as well as glass-ionomer cement (Fu ≈ 100 N), resulted in rather low retention forces. Zinc phosphate cement guaranteed high retention forces. After aging, retention was sufficient only for cementation with zinc phosphate cement and for the combination of sandblasted abutments and glass-ionomer cement. CONCLUSIONS: When glass-ionomer cement is used to fix cantilever FDPs on implants, sandblasting of standard titanium abutments may help prevent loss of retention. Retention forces were still high for FDPs fixed with zinc phosphate cement, even when the abutments were not pretreated. Use of permanent cements only, however, is recommended to prevent unwanted loosening of cantilever FDPs.

Single mandibular implant study (SMIS) - masticatory performance - results from a randomized clinical trial using two different loading protocols.

OBJECTIVES: This multi-centre randomized controlled trial was conducted to investigate, whether the masticatory performance of elderly edentulous patients is improved by placement of a single implant in the midline of the edentulous mandible, and whether improvements differ with respect to the loading protocol, i.e., implant is loaded either directly or three months later after second stage surgery. METHODS: Edentulous seniors aged 60-89 years were screened according to inclusion and exclusion criteria and 163 underwent implant placement. Of those, 158 were randomly assigned either to the direct loading group A (n=81) or the conventional loading group B (n=77). Chewing efficacy was obtained before treatment, one month after implant placement during the submerged healing phase (only group B) and 1 and 4 months after implant loading. RESULTS: The masticatory performance increased over time in both groups. Four months after loading, a significant increase was observed for both groups compared to the baseline data without implant (p≤0.05). However, between the two groups, chewing efficiency did not differ significantly at any point in time (p>0.05). CONCLUSIONS: A single midline implant in the edentulous mandible increases masticatory performance significantly, independently from the loading protocol. CLINICAL SIGNIFICANCE: A single midline implant in the edentulous mandible increases masticatory performance. The loading protocol has no influence.

Immediate and delayed loading of two-piece reduced-diameter implants with locator-analog attachments in edentulous mandibles: One-year results from a randomized clinical trial examining clinical outcome and patient expectation.

BACKGROUND: Prosthetic management of thin alveolar ridges in the edentulous mandibles of elderly patients, especially the time of loading, the number of implants needed, and patient expectations and perception, is a challenge in implant dentistry. PURPOSE: Survival of conventionally and immediately loaded 2-piece reduced-diameter implants in the interforaminal region of the edentulous mandible supporting locator-analog attachments was evaluated. Prosthetic complications and peri-implant hygiene were also studied, and patient expectation and subjective evaluation of the treatment were documented. MATERIAL AND METHODS: Twenty-five patients with adapted complete dentures received 4 reduced-diameter implants. All anterior implants were immediately loaded. Three months later, patients were allocated by randomization to 1 of 2 treatment groups: 2 locator-analog attachments on the anterior implants (Group A); or 4 locator-analog attachments (Group B). After another 3 months patient allocation was changed (crossover design) for the next 3 months. Questionnaires with Likert scales and numeric rating scales were used to assess patients' expectations and subjective overdenture-related variables, respectively. RESULTS: One implant was lost in the immediate-loading group. Survival was 98% and 100% for immediate and delayed loading, respectively. During 12-month observation, 8 complications required aftercare. At the beginning of treatment, patients' expectations were highly positive. Subjective assessment of overdenture-related variables 3 months after immediate loading of 2 implants revealed a statistically significant improvement for most of the variables studied; this was maintained 1 year later. In the subjective assessments, there were no statistically significant differences between Groups A and B. CONCLUSION: Immediate loading of reduced-diameter implants supporting locator-analog attachments resulted in high implant survival, few prosthetic complications, good oral hygiene, and improvement of subjective denture perception in the short-term. It might be a promising treatment option, especially for elderly patients with a narrow mandibular ridge.

Cemented Single Crown Retention on Dental Implants: An In Vitro Study.

PURPOSE: The aim of this study was to determine the influence of selected cements, abutment heights, and aging on the retention of zirconia crowns on zirconia abutments. MATERIALS AND METHODS: Zirconia crowns and abutments (height: 4.0 or 5.5 mm) were sandblasted and retained using five different cements. Axial pull-off tests were performed after thermocycling or 3 days of water storage. RESULTS: An increase in abutment height was associated with an increase in decementation force when permanent cementation was tested. The aging protocol showed that temporarily cemented crowns showed a significant retention decrease, while use of a permanent cement led to a moderate increase. CONCLUSION: Only use of permanent cements ensures clinically adequate decementation forces.

Single Mandibular Implant Study: Recruitment Considerations.

PURPOSE: The aim of this multicenter single mandibular implant study was to compare the clinical outcome of an immediately loaded implant placed in the midline of an edentulous mandible with the clinical outcome when closed healing and delayed loading is chosen. Here, the patient recruitment period and the main reasons for exclusion were analyzed. MATERIALS AND METHODS: Patient recruitment was performed at nine German universities. Rather conservative inclusion and exclusion criteria, including denture satisfaction, denture status, a psychologic symptom checklist, and a defined bone height in the posterior mandible, had to be fulfilled. It was initially calculated that 230 persons would have to be screened within 13 months to include 180 persons in the trial. RESULTS: Within 13 months (December 2012 to December 2013), 201 patients were screened for possible inclusion in the trial and 148 met the inclusion criteria. Finally, after the recruitment period was extended by 2.5 months, 224 patients were screened and 169 were included. Of those screened, 55 (24.6%) did not meet the inclusion criteria and were excluded. Another 4 patients (1.8%) were excluded based on their psychologic symptom checklist score, while 5 others (2.8%) showed signs of noncompliance. A further 8 patients (4.4%) decided not to participate and withdrew their informed consent, and another 3 (1.3%) were no longer available after screening. Another 2 patients were excluded due to medical contraindications and 1 due to an insufficient mandibular denture. In 34 cases (15.2%), the residual bone height did not comply with McGarry type II or III. CONCLUSION: Within the limitations of this patient recruitment period, it can be concluded that residual bone height is the most important factor when considering elderly edentulous patients for implant therapy. The psychologic symptom checklist score was less important.

Functional adaptation of the masticatory system to implant-supported mandibular overdentures.

OBJECTIVES: The purpose of this study was to investigate the adaptation behavior of the stomatognathic system after immediate loading (24 to 72 h after surgery) of two implants supporting mandibular overdentures, assessed on insertion and three months later. The study hypothesis was that insertion of the overdentures would significantly change masticatory performance and muscle activity at both times. MATERIAL AND METHODS: Thirty subjects (nine female, mean age 69.64 ± 11.81 years; 21 male, mean age 68.67 ± 7.41 years) who participated in a randomized clinical trial were included in the study. Each patient was examined three times: (i) at baseline, after already having worn new dentures for three months (T1); (ii) immediately after insertion of the overdentures on the implants (T2); and (iii) after an adaptation period of three months (T3). Examination comprised assessment of masticatory performance with artificial test food (Optocal), and simultaneous bilateral surface EMG recording of the masseter and anterior temporalis muscles. Particle-size distribution (representative value X50 ), maximum muscle contraction (MVC), and total muscle work (TMW; area under the curve) were compared by use of repeated-measures analysis of variance (ANOVA). RESULTS: At T3, all measured variables (i.e., masticatory performance and muscle activity) were significantly different from those at T1. At T2, no significant changes were observed. The study hypothesis had to be rejected for T2 but accepted for T3. CONCLUSION: Functional rehabilitation (in terms of masticatory performance and masticatory muscle activity) does not occur immediately after immediate loading of two implants with mandibular overdentures, but requires a significant time for functional improvement.

Effect of prosthetic restoration on implant survival and success.

PURPOSE: The objective of this work was to evaluate the effect of prosthetic restoration on the survival of implants and on the incidence of implant-related complications. MATERIAL AND METHODS: From a prospectively documented clinical study, 1569 implants placed in 630 patients (mean age 59.56 years) were evaluated. Selection criteria were a conventional loading protocol, prosthetic restoration with at least one follow-up, and a minimum observation period of 9 months. Implants that failed before prosthetic restoration were excluded. The sample included 1345 tissue-level implants and 104 bone-level implants (Straumann), and 120 Replace implants (Nobel Biocare). The observation period ranged between 9 months and 11 years after prosthetic restoration (mean 4.0 years; SD 2.5). The implants were restored with single crowns (n = 557), fixed dental prostheses (n = 594), or removable dental prostheses (RDP) (n = 418). In the RDP group, 356 implants were restored with telescoping crowns, 22 with bar units 24 with bar joints, and 16 with locator attachments. The incidence of implant-related complications and failures was analyzed by use of Kaplan-Meier survival curves. Cox regression analysis was used to identify possible risk factors. RESULTS: Twenty-seven failures (1.8%; loosened or removed implants) were observed after prosthetic restoration; the incidence of failure was 3% for implants placed in males and 1% for implants placed in females. Other factors had no effect on the incidence of failure. Peri-implantitis (n = 29) and marginal bone loss >2 mm without acute inflammation (n = 6) also resulted in a 4% incidence of severe implant-related complications (62 of 1569; success 96%). Cox regression analysis revealed combined tooth-implant-supported restorations as a significant risk-reducing factor for severe implant-related complications (hazard ratio, HR = 0.34; P = 0.04). There was, furthermore, a tendency toward a greater incidence of complications for implants restored with RDPs than for single crowns (P = 0.08). Other factors, for example location (anterior/posterior, maxilla/mandible), age, sex, or implant placement combined with bone augmentation, had no significant effect on the incidence of implant-related complications (P values ranging between 0.16 and 0.94). CONCLUSIONS: The type of support has a small but significant effect on implant prognosis. For detailed analysis of the effects of loading by different types of prosthetic restoration, larger sample sizes are required.

Spatially resolved analysis of plutonium isotopic signatures in environmental particle samples by laser ablation-MC-ICP-MS.

Laser ablation-multi-collector-inductively coupled plasma mass spectrometry (LA-MC-ICP-MS) was optimized and investigated with respect to its performance for determining spatially resolved Pu isotopic signatures within radioactive fuel particle clusters. Fuel particles had been emitted from the Chernobyl nuclear power plant (ChNPP) where the 1986 accident occurred and were deposited in the surrounding soil, where weathering processes caused their transformation into radioactive clusters, so-called micro-samples. The size of the investigated micro-samples, which showed surface alpha activities below 40 mBq, ranged from about 200 to 1000 µm. Direct single static point ablations allowed to identify variations of Pu isotopic signatures not only between distinct fuel particle clusters but also within individual clusters. The resolution was limited to 100 to 120 µm as a result of the applied laser ablation spot sizes and the resolving power of the nuclear track radiography methodology that was applied for particle pre-selection. The determined (242)Pu/(239)Pu and (240)Pu/(239)Pu isotope ratios showed a variation from low to high Pu isotope ratios, ranging from 0.007(2) to 0.047(8) for (242)Pu/(239)Pu and from 0.183(13) to 0.577(40) for (240)Pu/(239)Pu. In contrast to other studies, the applied methodology allowed for the first time to display the Pu isotopic distribution in the Chernobyl fallout, which reflects the differences in the spent fuel composition over the reactor core. The measured Pu isotopic signatures are in good agreement with the expected Pu isotopic composition distribution that is typical for a RBMK-1000 reactor, indicating that the analyzed samples are originating from the ill-fated Chernobyl reactor. The average Pu isotope ratios [(240)Pu/(239)Pu = 0.388(86), (242)Pu/(239)Pu = 0.028(11)] that were calculated from all investigated samples (n = 48) correspond well to previously published results of Pu analyses in contaminated samples from the vicinity of the Chernobyl NPP [e.g. (240)Pu/(239)Pu = 0.394(2) and (242)Pu/(239)Pu = 0.027(1); Nunnemann et al. (J Alloys Compd 271-273:45-48, 1998)].

Immediate Loading of Dental Implants in Edentulous Mandibles by Use of Locator® Attachments or Dolder® Bars: Two-Year Results from a Prospective Randomized Clinical Study.

PURPOSE: The study aims to evaluate survival and incidence of complications for pairs of implants placed in the front region of edentulous mandibles and immediately loaded with either bar or Locator attachments. MATERIALS AND METHODS: Forty-six patients with edentulous mandibles (mean age 69.4 years at inclusion in the study; 73.9% male) received two implants in the interforaminal area of the symphysis. Dolder bar or Locator attachments, allocated randomly, were then attached immediately, and both clips and a framework were fastened to the denture by the dental technician within 72 hours. RESULTS: During the first 3 months of the 2-year period of observation, eight implants in five patients were lost, and were removed. Survival was 89.1% and 93.5% for the bar and Locator groups, respectively. During the entire period of observation, 38 prosthetic complications required aftercare. Five dentures had to be removed or reworked after implant failure, but no superstructure was lost or had to be remade for prosthetic reasons. Survival of the original dentures was 93.5% and 95.7% for the bar and Locator groups, respectively. CONCLUSION: Within the limitations of this study, results from immediate loading of two implants in the edentulous mandible with either Locator or bar attachments hardly differed. Prosthetic complications and aftercare measures in the Locator group were frequent but easy to handle. Ease of repair and cleaning, in particular, might be reasons for choosing the single-attachment system.